How to make Italian Inspired Prosciutto Basil Panini

This is the essence I longed to capture when I first decided to create the Italian Inspired Prosciutto Basil Panini. It’s a recipe born from a desire to weave the rustic elegance of Italy into the fabric of everyday life, to transform a humble sandwich into a work of art that speaks to the soul.

The panini cradles the delicate yet distinct flavors of thinly sliced prosciutto, the sweet aroma of basil leaves, and the creamy embrace of mozzarella cheese. Each element is chosen with care, each ingredient an ode to the timeless traditions of Italian cooking. The warmth of the pressed bread, with its golden-brown crust, promises a moment of escape, a brief sojourn to the cobblestone streets and rolling hills of a faraway land.

This dish is more than just sustenance; it’s a celebration of life’s simple joys. It’s for those afternoons when you crave the comfort of good food and the company of loved ones, for the times when you wish to indulge in the luxury of flavors without stepping away from the coziness of your own kitchen. So let us savor the journey together, one bite at a time, as we explore the charm of the Italian Inspired Prosciutto Basil Panini—a sandwich that wraps the spirit of Italy in the warmth of home.

Italian Inspired Prosciutto Basil Panini Recipe

Delicious Prosciutto Sandwich (Panino) With Mozzarella, Tomato and Basil -  Pina Bresciani

Italian Inspired Prosciutto Basil Panini

The Italian Inspired Prosciutto Basil Panini is a celebration of the vibrant flavors of Italy, encapsulated in a warm, pressed sandwich. It features the delicate saltiness of thinly sliced prosciutto, paired with the fresh, aromatic lift of basil leaves. This panini is further enhanced by the creamy texture and subtle tang of mozzarella cheese, which melts beautifully as the sandwich grills to golden perfection. The choice of bread is crucial, often a ciabatta or a baguette, to provide the necessary crispness and sturdiness to contain the rich fillings. This panini is a testament to the simplicity of Italian cooking, where high-quality ingredients are allowed to shine, creating a meal that is both satisfying and evocative of the Mediterranean lifestyle. It's an ideal option for a quick yet sophisticated lunch or a delightful dinner that brings a touch of Italy to your table.
Prep Time 10 minutes
Cook Time 10 minutes
Total Time 20 minutes
Course Main Course
Cuisine Italian
Servings 4 people
Calories 359 kcal


  • 1 small bowl
  • 1 grill


  • olive oil 1/2 cup
  • balsamic vinegar 3 tbsp.
  • garlic 1 clove, minced
  • prosciutto 8 oz., thinly sliced
  • mozzarella cheese 10 oz., thinly sliced
  • tomato 12 slices
  • basil 12 large leaves
  • ciabatta bread 16oz., halved horizontally


  • Whisk garlic, vinegar and olive oil in small bowl to blend; use salt and pepper to season dressing to taste.
  • Layer basil, tomato, mozzarella and prosciutto over bottom of bread.
  • Drizzle the dressing lightly on the sandwich and season once more with salt and pepper. Top with the remaining slice of bread then slice into 4 quarters.
  • Preheat your barbecue to medium heat. Set the sandwiches to grill for about 5 minutes on each side or until beautifully golden brown with melted cheese. Press occasionally with a large spatula to compact.
  • Enjoy!


Keyword balsamic vinegar, mozzarella cheese, prosciutto

How to make Italian Inspired Prosciutto Basil Panini using oven

Prosciutto and Mozzarella Sandwich - Lena's Kitchen

The Italian Inspired Prosciutto Basil Panini is a symphony of flavors, each note from the salty prosciutto to the peppery basil creating a harmonious melody in your mouth. This panini whispers tales of quaint cobblestone streets and the rustic charm of the Italian countryside. Making it in an oven, rather than a panini press, is like uncovering a hidden path to a secret garden – unconventional yet serendipitously delightful.

As the bread crisps to golden perfection in the warmth of the oven, the anticipation builds. The aroma of melting cheese intertwined with the earthy scent of basil fills the kitchen, evoking a sense of comfort and joy. It’s a simple pleasure, crafting such a sandwich, and the result is a testament to the beauty found in simplicity. This panini isn’t just food; it’s a moment of escape, a bite-sized vacation to Italy, served right on your plate with love and a touch of whimsy.

Tips for making Italian Inspired Prosciutto Basil Panini

Prosciutto Sandwich with Mozzarella & Tomato

Cooking Tips

This sandwich, with its thin slices of prosciutto, fresh basil, and mozzarella cheese, captures the essence of Italian cuisine—where quality ingredients speak for themselves. The panini’s charm lies in the delicate balance of flavors and textures: the saltiness of the prosciutto, the creamy melt of the mozzarella, and the aromatic freshness of basil leaves.

When crafting such a panini, it’s essential to consider the bread as the foundation of this edible masterpiece. A good ciabatta or focaccia, when toasted to just the right degree of golden crispness, provides a satisfying crunch that gives way to the tender fillings within. It’s a sensory delight that starts with the ears and carries through to the last bite.

One of my personal tips for elevating this panini is to drizzle a touch of extra virgin olive oil over the inside of the bread before assembling. It adds a subtle fruitiness that complements the prosciutto beautifully. Another suggestion is to use only the freshest basil you can find; its bright, peppery notes are integral to the panini’s character.

As you press the sandwich in a hot panini grill or on a skillet, the anticipation builds with the scent of warming cheese and cured meat filling the air. There’s a certain joy in watching the ingredients come together, melting and melding into something greater than the sum of their parts. Serving this panini isn’t just about feeding the body; it’s about offering a moment of culinary bliss, an escape to a quaint Italian café, if only during lunch.

Serving suggestions

Mozz Prosciutto Sandwich w Garlic Basil Aioli | A-Yo Kitchen

The Italian Inspired Prosciutto Basil Panini is a symphony of flavors that sings of sun-drenched afternoons in a quaint Tuscan village. It’s the kind of meal that whispers of leisurely lunches, where time seems to stand still and every bite is savored. The saltiness of the prosciutto, paired with the sweet freshness of basil, creates a harmonious interplay that is both grounding and uplifting.

When considering how to serve this delightful panini, I’m drawn to the simplicity and elegance that embody Italian cuisine. A side of marinated olives or artichoke hearts could complement the sandwich, adding a touch of brininess or a tender bite that echoes the rustic charm of the countryside. For a more substantial accompaniment, a crisp arugula salad dressed lightly with extra virgin olive oil and a squeeze of lemon would provide a peppery contrast to the rich, savory flavors of the panini.

In moments of reflection, I find that this panini pairs beautifully with the conviviality of good company. Imagine sharing this meal on a terrace, laughter mingling with the clink of chilled glasses, perhaps filled with a sparkling Prosecco or a light-bodied Chianti. It’s not just about feeding the body but nourishing the soul with the joy that comes from a meal made with love and shared with others.

The Prosciutto Basil Panini isn’t merely a sandwich; it’s an invitation to embrace the warmth of connection and the art of living well. So let us gather around the table with hearts as open as our appetites, ready to partake in the simple pleasure of a meal crafted with intention and served with a spirit of generosity.

Top 5 FAQs about Italian Inspired Prosciutto Basil Panini

  • What bread is best for a prosciutto basil panini? For the best results, a sturdy Italian bread like ciabatta or focaccia is ideal. These types of bread have a firm crust and porous texture that absorbs flavors well and holds up under the heat and pressure of a panini press without becoming too soggy or falling apart.
  • How do you balance the flavors in a prosciutto basil panini? Balancing the flavors involves using the right amount of each ingredient. Prosciutto is salty and rich, so it should be complemented by the freshness of basil, the creaminess of mozzarella or another mild cheese, and the tanginess of a condiment like balsamic glaze or a touch of olive oil and vinegar. Some may add tomato for acidity or arugula for a peppery bite.
  • What is the proper technique for pressing a panini? Preheat your panini press or a heavy skillet. Assemble your sandwich and if you’re using a skillet, you might need another heavy skillet or a panini press weight to apply pressure on top. Cook until the bread is toasted to a golden-brown color and the cheese has melted, usually about 3 to 5 minutes per side, depending on the heat of your press or skillet.
  • Can you make a prosciutto basil panini without a panini press? Yes, you can use a grill pan or a regular skillet along with something heavy like another pan or a brick wrapped in foil to press down the sandwich. Cook on medium heat and press down firmly to achieve the characteristic panini texture.
  • What are some common variations or additions to a prosciutto basil panini? Variations can include different cheeses such as provolone or fontina, the addition of vegetables like roasted red peppers or artichoke hearts, or using pesto instead of fresh basil. Some might also include sliced chicken breast for extra protein or swap out the prosciutto for another type of cured meat.

In the realm of Italian-inspired sandwiches, the Prosciutto Basil Panini stands as a testament to the harmony of simple ingredients elevated to something sublime. The conclusion of any discourse on this sandwich must acknowledge the sheer pleasure derived from the interplay of its components. The saltiness of the prosciutto, paired with the peppery freshness of basil, creates a dance of flavors that is both grounding and exhilarating. The crusty exterior of the panini bread, with its satisfying crunch, gives way to the warm, yielding interior, making each bite a textural delight.

The Prosciutto Basil Panini is not just a sandwich; it’s a celebration of Italian culinary ethos—where quality ingredients speak for themselves and the art of food is practiced with reverence and joy. It’s the kind of meal that doesn’t just satiate hunger but also stirs the soul, reminding us of the beauty found in simplicity. Whether enjoyed in a sun-dappled piazza or at your own kitchen table, this panini is a love letter to the timeless flavors of Italy, inviting you to pause and savor life’s delicious moments.

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